The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pleuroparenchymal fibroelastosis (PPFE)
Publications
Pleuroparenchymal fibroelastosis: one more walk on the wild side of drugs?
The European respiratory journal 2014 Aug;44;289-96 — 2014 Aug — 289-96
Ofek E, Sato M, Saito T, Wagnetz U, Roberts HC, Chaparro C, Waddell TK, Singer LG, Hutcheon MA, Keshavjee S, Hwang DM
Restrictive allograft syndrome post lung transplantation is characterized by pleuroparenchymal fibroelastosis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2013 Mar;26;350-6 — 2013 Mar — 350-6