The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLVI.e

Fat/oil embolism - The FES embolism syndrome

Publications

Mendoza-Morales RC, Camberos-Nava EV, Luna-Rosas A, Garcés-Ramírez L, De la Cruz F, García-Dolores F

A fatal case of systemic fat embolism resulting from gluteal injections of vitamin e for cosmetic enhancement.

Forensic science international 2016 Feb;259;e1-4 — 2016 Feb — e1-4

Hjort M, Hoegberg LC, Almind M, Jansen T

Subacute fat-embolism-like syndrome following high-volume intramuscular and accidental intravascular injection of mineral oil.

Clinical toxicology (Philadelphia, Pa.) 2015 May;53;230-2 — 2015 May — 230-2

Hain JR

Subcutaneous corn oil injections, fat embolization syndrome, and death.

The American journal of forensic medicine and pathology 2009 Dec;30;398-402 — 2009 Dec — 398-402