The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Publications

Harris ZM, Antin-Ozerkis D

An 84-Year-Old Physician With Progressive Dyspnea and Bilateral Upper Lobe Opacities.

Chest 2021 May;159;e325-e329 — 2021 May — e325-e329

Guerrero Gómez DA, París Zorro S, Aponte Barrios W, Carrillo Bayona JA

Drug reaction with eosinophilia and systemic symptoms (DRESS) with severe and atypical lung involvement.

Radiology case reports 2020 Nov;15;2178-2182 — 2020 Nov — 2178-2182

Sandler R, Sandberg H

Naproxen and the occurrence of eosinophilic pneumonia.

American family physician 1993 Nov 01;48;1023 — 1993 Nov 01 — 1023

Nader DA, Schillaci RF

Pulmonary infiltrates with eosinophilia due to naproxen.

Chest 1983 Feb;83;280-2 — 1983 Feb — 280-2

Buscaglia AJ, Cowden FE, Brill H

Pulmonary infiltrates associated with naproxen.

JAMA 1984 Jan 06;251;65-6 — 1984 Jan 06 — 65-6

Londino AV, Wolf GL, Calabro JJ, Perrone SJ

Naproxen and pneumonitis.

JAMA 1984 Oct 12;252;1853 — 1984 Oct 12 — 1853

Sheehan NJ

Pulmonary infiltrates and eosinophilia associated with naproxen.

British journal of rheumatology 1985 Aug;24;302-3 — 1985 Aug — 302-3

Flint KC, Johnson NM

Pulmonary eosinophilia associated with naproxen therapy.

Journal of the Royal Society of Medicine 1987 Feb;80;120-1 — 1987 Feb — 120-1

Ogawa H, Kurashima K, Namura M, Kanaya H, Kawamura Y, Ohka T, Kurumaya H, Yasui M, Fujimura M, Matsuda T

Pulmonary infiltrates with eosinophilia due to naproxen.

Japanese journal of medicine 1991 Jan-Feb;30;32-4 — 1991 Jan-Feb — 32-4

Goodwin SD, Glenny RW

Nonsteroidal anti-inflammatory drug-associated pulmonary infiltrates with eosinophilia. Review of the literature and Food and Drug Administration Adverse Drug Reaction reports.

Archives of internal medicine 1992 Jul;152;1521-4 — 1992 Jul — 1521-4