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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.g

Pulmonary fibrosis

Publications

Hallee TJ

Diffuse lung disease caused by inhalation of mercury vapor.

The American review of respiratory disease. 1969;99(3):430-6

Carrington CB

Organizing interstitial pneumonia. Definition of the lesion and attempts to devise an experimental model.

The Yale journal of biology and medicine. 1968;40(5-6):352-63

Lilis R, Miller A, Lerman Y

Acute mercury poisoning with severe chronic pulmonary manifestations.

Chest. 1985;88(2):306-9