The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Pleural effusion (uni- or bilateral) (can accompany DI-LDs)
Publications
Pleural effusions following cardiac injury and coronary artery bypass graft surgery.
Seminars in respiratory and critical care medicine 2001 Dec;22;657-64 — 2001 Dec — 657-64
Large pleural effusions occurring after coronary artery bypass grafting. Cardiovascular Surgery Associates, PC.
Annals of internal medicine 1999 Jun 01;130;891-6 — 1999 Jun 01 — 891-6