The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

VIII.c

Upper airway obstruction other than angioedema or hematoma

Publications

Patel RV, Cho C, Medd C, Cresswell J

Isolated non-hereditary angioneurotic oedema of uvula (Quincke's disease) in an adolescent.

BMJ case reports 2014 Apr 09;2014; — 2014 Apr 09

Bean-Lijewski JD

Glossopharyngeal nerve block for pain relief after pediatric tonsillectomy: retrospective analysis and two cases of life-threatening upper airway obstruction from an interrupted trial.

Anesthesia and analgesia 1997 Jun;84;1232-8 — 1997 Jun — 1232-8