The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLV.n

Hemopericardium - Bloody pericardial effusion

Publications

Nakanishi H, Kashiwase K, Nishio M, Wada M, Hirata A, Ueda Y

Recurrent pericardial effusion caused by pacemaker lead perforation and warfarin therapy at seven years after implantation.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2012 Feb;14;297 — 2012 Feb — 297

Hong YC, Chen YG, Hsiao CT, Kuan JT, Chiu TF, Chen JC

Cardiac tamponade secondary to haemopericardium in a patient on warfarin.

Emergency medicine journal : EMJ 2007 Sep;24;679-80 — 2007 Sep — 679-80

FELL SC, RUBIN IL, ENSELBERG CD, HURWITT ES

ANTICOAGULANT-INDUCED HEMOPERICARDIUM WITH TAMPONADE: ITS OCCURRENCE IN THE ABSENCE OF MYOCARDIAL INFARCTION OR PERICARDITIS.

The New England journal of medicine 1965 Apr 01;272;670-4 — 1965 Apr 01 — 670-4

Lee KS, Marwick T

Hemopericardium and cardiac tamponade associated with warfarin therapy.

Cleveland Clinic journal of medicine 1993 Jul-Aug;60;336-8 — 1993 Jul-Aug — 336-8