The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Hemopericardium - Bloody pericardial effusion
Publications
Pacemaker lead related myocardial perforation.
The American journal of emergency medicine 2021 Sep 04;; — 2021 Sep 04
Case Records of the Massachusetts General Hospital. Case 19-2015. A 71-Year-Old Man with Chest Pain and Shortness of Breath.
The New England journal of medicine 2015 Jun 18;372;2438-46 — 2015 Jun 18 — 2438-46
Pacemaker lead perforation causing hemopericardium eight years after implantation.
Indian heart journal 2013 May-Jun;65;331-3 — 2013 May-Jun — 331-3
Incidence and predictors of pericardial effusion after permanent heart rhythm device implantation: prospective evaluation of 968 consecutive patients.
Circulation journal : official journal of the Japanese Circulation Society 2013;77;975-81 — 2013 — 975-81