The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.e

ARDS - Acute lung injury

Publications

Silvestri RC, Huseby JS, Rughani I, Thorning D, Culver BH

Respiratory distress syndrome from lymphangiography contrast medium.

The American review of respiratory disease 1980 Oct;122;543-9 — 1980 Oct — 543-9

Pemberton LB

Shock lung with massive tracheal loss of plasma.

JAMA 1977 Jun 06;237;2511-3 — 1977 Jun 06 — 2511-3