The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XII.u

Cardiac- cardiorespiratory/pulmonary arrest

Publications

Baldo BA

Adverse events to monoclonal antibodies used for cancer therapy: Focus on hypersensitivity responses.

Oncoimmunology 2013 Oct 01;2;e26333 — 2013 Oct 01 — e26333

Giezen TJ, Mantel-Teeuwisse AK, Straus SM, Schellekens H, Leufkens HG, Egberts AC

Safety-related regulatory actions for biologicals approved in the United States and the European Union.

JAMA 2008 Oct 22;300;1887-96 — 2008 Oct 22 — 1887-96

Ibrahim EM, Zeeneldin AA, Al-Gahmi AM, Sallam YA, Fawzi EE, Bahadur YA

Safety and efficacy of cetuximab-chemotherapy combination in Saudi patients with metastatic colorectal cancer.

Indian journal of cancer 2007 Apr-Jun;44;56-61 — 2007 Apr-Jun — 56-61