The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.z

Progression, acceleration or exacerbation of preexisting ILD/fibrosis

Publications

Tomassetti S, Ruy JH, Gurioli C, Ravaglia C, Buccioli M, Tantalocco P, Decker PA, Cavazza A, Dubini A, Agnoletti V, Gurioli C, Casoni GL, Romagnoli M, Poletti V

?The effect of anticoagulant therapy for idiopathic pulmonary fibrosis in real life practice.

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 2013 Aug 01;30;121-7 — 2013 Aug 01 — 121-7