The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

Publications

Oishi Y, Sando Y, Tajima S, Maeno T, Maeno Y, Sato M, Hosono T, Suga T, Kurabayashi M, Nagai R

Indomethacin induced bulky lymphadenopathy and eosinophilic pneumonia.

Respirology (Carlton, Vic.) 2001 Mar;6;57-60 — 2001 Mar — 57-60

Rossi SE, Erasmus JJ, McAdams HP, Sporn TA, Goodman PC

Pulmonary drug toxicity: radiologic and pathologic manifestations.

Radiographics : a review publication of the Radiological Society of North America, Inc 2000 Sep-Oct;20;1245-59 — 2000 Sep-Oct — 1245-59