The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.i

Flash (fulminate) pulmonary edema

Publications

Bristedt P, Tylén U

Pulmonary edema following intravenous injection of nonionic low-osmolar contrast medium--appearance on HRCT. A case report.

Acta radiologica (Stockholm, Sweden : 1987). 1998;39(1):81-3

Vandenplas O, Hantson P, Dive A, Mahieu P

Fulminant pulmonary edema following intravenous administration of radiocontrast media.

Acta clinica Belgica. 1990;45(5):334-9

Kozlowski C, Kollef MH

Noncardiogenic pulmonary edema associated with intravenous radiocontrast administration.

Chest. 1992;102(2):620-1