The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Severe or catastrophic bronchospasm or asthma attack (can be fatal)
Publications
[Asthma and heroin use].
Presse medicale (Paris, France : 1983) 2017 Jul - Aug;46;660-675 — 2017 Jul - Aug — 660-675
Near Fatal Asthma in an Inner City Population.
American journal of therapeutics 2016 Nov/Dec;23;e1375-e1380 — 2016 Nov/Dec — e1375-e1380
Life-threatening asthma after heroin inhalation. A case report and a review of the literature.
Acta bio-medica : Atenei Parmensis 2010 Dec;81;63-7 — 2010 Dec — 63-7
Inhaled heroin causing a life-threatening asthma exacerbation and marked peripheral eosinophilia.
British journal of hospital medicine (London, England : 2005) 2007 Jun;68;332-3 — 2007 Jun — 332-3
The effects of cocaine and heroin use on intubation rates and hospital utilization in patients with acute asthma exacerbations.
Chest 2005 Oct;128;1951-7 — 2005 Oct — 1951-7
Heroin insufflation as a trigger for patients with life-threatening asthma.
Chest 2003 Feb;123;510-7 — 2003 Feb — 510-7
Inhaled heroin-induced status asthmaticus: five cases and a review of the literature.
Chest 2000 Jan;117;272-5 — 2000 Jan — 272-5