The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Cough (lone)
Publications
Comparison of the incidence of imidapril and enalapril induced cough.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet. 2010;93 Suppl 1:S48-53
ACE-inhibitor-induced cough, an adverse drug reaction unrecognised for several years: studies in prescription-event monitoring.
European journal of clinical pharmacology. 1996;49(6):431-7
Cough and wheeze caused by inhibitors of angiotensin-converting enzyme.
The New England journal of medicine. 1986;314(1):61
Enalapril-induced cough.
Archives of internal medicine. 1989;149(12):2701-3
[Intractable cough from enalapril].
Anales de medicina interna (Madrid, Spain : 1984). 1991;8(12):628