The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
DRES syndrome - DRESS-like reaction
Publications
Drug reaction with eosinophilia and systemic symptoms (DRESS) with severe and atypical lung involvement.
Radiology case reports 2020 Nov;15;2178-2182 — 2020 Nov — 2178-2182
Piñana E, Lei SH, Merino R, Melgosa M, De La Vega R, Gonzales-Obeso E, Ramírez E, Borobia A, Carcas A
DRESS-syndrome on sulfasalazine and naproxen treatment for juvenile idiopathic arthritis and reactivation of human herpevirus 6 in an 11-year-old Caucasian boy.
Journal of clinical pharmacy and therapeutics 2010 Jun;35;365-70 — 2010 Jun — 365-70
Hypersensitivity reactions to non-steroidal anti-inflammatory drugs.
Current drug metabolism 2009 Nov;10;971-80 — 2009 Nov — 971-80
De Weck AL, Sanz ML, Gamboa PM, Aberer W, Blanca M, Correia S, Erdman S, Jermann JM, Kanny G, Kowalski M, Mayorga L, Medrala W, Merk A, Sturm GJ, Sainte-Laudy J, Schneider MS, Sczczeklik A, Weber JM, Wedi A
Nonsteroidal anti-inflammatory drug hypersensitivity syndrome. A multicenter study. I. Clinical findings and in vitro diagnosis.
Journal of investigational allergology & clinical immunology 2009;19;355-69 — 2009 — 355-69