The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIX.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Amano H, Kitagawa Y, Hayakawa T, Muto T, Okumura A, Iwayama H

Methylprednisolone-induced anaphylaxis diagnosed by intradermal skin test: a case report.

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 2021 Jul 13;17;70 — 2021 Jul 13 — 70

Chung JH, Ahn KR, Chun HJ, Kim CS, Kang KS, Yoo SH, Chung JW

Allergic reactions after intravenous injection of methylprednisolone: A case report.

Korean journal of anesthesiology 2009 Oct;57;499-502 — 2009 Oct — 499-502

Porcaro F, Paglietti MG, Diamanti A, Petreschi F, Schiavino A, Negro V, Pecora V, Fiocchi A, Cutrera R

Anaphylactic shock with methylprednisolone sodium succinate in a child with short bowel syndrome and cow's milk allergy.

Italian journal of pediatrics 2017 Nov 17;43;104 — 2017 Nov 17 — 104

Levy Y, Segal N, Nahum A, Marcus N, Garty BZ

Hypersensitivity to methylprednisolone sodium succinate in children with milk allergy.

The journal of allergy and clinical immunology. In practice 2014 Jul-Aug;2;471-4 — 2014 Jul-Aug — 471-4

Ben Said B, Leray V, Nicolas JF, Rozieres A, Berard F

Methylprednisolone-induced anaphylaxis: diagnosis by skin test and basophil activation test.

Allergy 2010 Apr;65;531-2 — 2010 Apr — 531-2

Nahum A, Garty BZ, Marcus N, Shoenfeld T, Levy Y

Severe hypersensitivity reactions to corticosteroids in children.

Pediatric emergency care 2009 May;25;339-41 — 2009 May — 339-41

Nakamura H, Matsuse H, Obase Y, Mitsuta K, Tomari S, Saeki S, Kawano T, Kondo Y, Machida I, Shimoda T, Asai S, Kohno S

Clinical evaluation of anaphylactic reactions to intravenous corticosteroids in adult asthmatics.

Respiration; international review of thoracic diseases 2002;69;309-13 — 2002 — 309-13

Schonwald S

Methylprednisolone anaphylaxis.

The American journal of emergency medicine 1999 Oct;17;583-5 — 1999 Oct — 583-5

Mace S, Vadas P, Pruzanski W

Anaphylactic shock induced by intraarticular injection of methylprednisolone acetate.

The Journal of rheumatology 1997 Jun;24;1191-4 — 1997 Jun — 1191-4

McNamara RM

Anaphylaxis after intravenous corticosteroid administration.

The Journal of emergency medicine 1986;4;213-5 — 1986 — 213-5

Laine-Cessac P, Moshinaly H, Gouello JP, Geslin P, Allain P

[Severe anaphylactoid reactions after intravenous corticosteroids. Report of a case and review of the literature].

Therapie 1990 Nov-Dec;45;505-8 — 1990 Nov-Dec — 505-8