The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

I.i

Subclinical pulmonary infiltrates/ILD

Publications

Jakacki RI, Schramm CM, Donahue BR, Haas F, Allen JC

Restrictive lung disease following treatment for malignant brain tumors: a potential late effect of craniospinal irradiation.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1995 Jun;13;1478-85 — 1995 Jun — 1478-85