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The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Schuster C, Wüthrich B

Anaphylactic drug reaction to celecoxib and sulfamethoxazole: cross reactivity or coincidence?

Allergy. 2003;58(10):1072

Gagnon R, Julien M, Gold P

Selective celecoxib-associated anaphylactoid reaction.

The Journal of allergy and clinical immunology. 2003;111(6):1404-5

Wiholm BE

Identification of sulfonamide-like adverse drug reactions to celecoxib in the World Health Organization database.

Current medical research and opinion. 2001;17(3):210-6