The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

IV.a

Bronchospasm - Wheezing - Asthma

Publications

Schaller A, Metz-Favre C, Guenard-Bilbaut L, De Blay F

[Is celecoxib a safe alternative for the Fernand Widal syndrome?].

Revue des maladies respiratoires. 2018;35(2):149-159

Kim YJ, Lim KH, Kim MY, Jo EJ, Lee SY, Lee SE, Yang MS, Song WJ, Kang HR, Park HW, Chang YS, Cho SH, Min KU, Kim SH

Cross-reactivity to Acetaminophen and Celecoxib According to the Type of Nonsteroidal Anti-inflammatory Drug Hypersensitivity.

Allergy, asthma & immunology research. 2014;6(2):156-62

Çelik GE, Erkekol FÖ, Aydın Ö, Demirel YS, Mısırlıgil Z

Are drug provocation tests still necessary to test the safety of COX-2 inhibitors in patients with cross-reactive NSAID hypersensitivity?

Allergologia et immunopathologia. 2013;41(3):181-8

Umemoto J, Tsurikisawa N, Nogi S, Iwata K, Oshikata C, Tatsuno S, Tanimoto H, Sekiya K, Tsuburai T, Mitomi H, Akiyama K

Selective cyclooxygenase-2 inhibitor cross-reactivity in aspirin-exacerbated respiratory disease.

Allergy and asthma proceedings. 2011;32(3):259-61

Baldassarre S, Schandene L, Choufani G, Michils A

Asthma attacks induced by low doses of celecoxib, aspirin, and acetaminophen.

The Journal of allergy and clinical immunology. 2006;117(1):215-7