The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLIV.h

Laryngospasm (a.k.a. laryngismus)

Publications

Potenza S, Nasti G, Ottaiano A, Filippelli A, Rossi F, Capuano A

Severe respiratory symptoms to oxaliplatin infusion: a case report of delayed hypersensitivity reaction.

Investigational new drugs 2010 Apr;28;185-6 — 2010 Apr — 185-6

Brandi G, Pantaleo MA, Galli C, Falcone A, Antonuzzo A, Mordenti P, Di Marco MC, Biasco G

Hypersensitivity reactions related to oxaliplatin (OHP).

British journal of cancer 2003 Aug 04;89;477-81 — 2003 Aug 04 — 477-81