The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

X.f

Anaphylaxis-Anaphylactoid reaction (can be fatal)

Publications

Davis PL

Anaphylactoid reactions to the nonvascular administration of water-soluble iodinated contrast media.

AJR. American journal of roentgenology. 2015;204(6):1140-5

Pradubpongsa P, Dhana N, Jongjarearnprasert K, Janpanich S, Thongngarm T

Adverse reactions to iodinated contrast media: prevalence, risk factors and outcome-the results of a 3-year period.

Asian Pacific journal of allergy and immunology. 2013;31(4):299-306

Khan NU, Shakeel N, Makda A, Mallick AS, Ali Memon M, Hashmi SH, Khan UR, Razzak JA

Anaphylaxis: incidence, presentation, causes and outcome in patients in a tertiary-care hospital in Karachi, Pakistan.

QJM : monthly journal of the Association of Physicians. 2013;106(12):1095-101

Brown SG, Stone SF, Fatovich DM, Burrows SA, Holdgate A, Celenza A, Coulson A, Hartnett L, Nagree Y, Cotterell C, Isbister GK

Anaphylaxis: clinical patterns, mediator release, and severity.

The Journal of allergy and clinical immunology. 2013;132(5):1141-1149.e5

Renaudin JM, Beaudouin E, Ponvert C, Demoly P, Moneret-Vautrin DA

Severe drug-induced anaphylaxis: analysis of 333 cases recorded by the Allergy Vigilance Network from 2002 to 2010.

Allergy. 2013;68(7):929-37

Pasternak JJ, Williamson EE

Clinical pharmacology, uses, and adverse reactions of iodinated contrast agents: a primer for the non-radiologist.

Mayo Clinic proceedings. 2012;87(4):390-402

Brockow K, Ring J

Anaphylaxis to radiographic contrast media.

Current opinion in allergy and clinical immunology. 2011;11(4):326-31

Yang MS, Lee SH, Kim TW, Kwon JW, Lee SM, Kim SH, Kwon HS, Park CH, Park HW, Kim SS, Cho SH, Min KU, Kim YY, Chang YS

Epidemiologic and clinical features of anaphylaxis in Korea.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2008;100(1):31-6

Greenberger PA, Rotskoff BD, Lifschultz B

Fatal anaphylaxis: postmortem findings and associated comorbid diseases.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2007;98(3):252-7

Low I, Stables S

Anaphylactic deaths in Auckland, New Zealand: a review of coronial autopsies from 1985 to 2005.

Pathology. 2006;38(4):328-32

Leone R, Conforti A, Venegoni M, Motola D, Moretti U, Meneghelli I, Cocci A, Sangiorgi Cellini G, Scotto S, Montanaro N, Velo G

Drug-induced anaphylaxis : case/non-case study based on an italian pharmacovigilance database.

Drug safety. 2005;28(6):547-56

Lang DM, Alpern MB, Visintainer PF, Smith ST

Elevated risk of anaphylactoid reaction from radiographic contrast media is associated with both beta-blocker exposure and cardiovascular disorders.

Archives of internal medicine. 1993;153(17):2033-40

Marshall GD Jr, Lieberman PL

Comparison of three pretreatment protocols to prevent anaphylactoid reactions to radiocontrast media.

Annals of allergy. 1991;67(1):70-4