The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.i

Negative pressure pulmonary edema (NPPE)

Publications

Horng HC, Ho MT, Huang CH, Yeh CC, Cherng CH

Negative pressure pulmonary edema following naloxone administration in a patient with fentanyl-induced respiratory depression.

Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists 2010 Sep;48;155-7 — 2010 Sep — 155-7