The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.e

ARDS - Acute lung injury

Publications

Prochilo T, Abeni C, Bertocchi P, Zaniboni A

Oxaliplatin-induced lung toxicity. Case report and review of the literature.

Current drug safety 2012 Apr;7;179-82 — 2012 Apr — 179-82

Pontes LB, Armentano DP, Soares A, Gansl RC

Fatal pneumonitis induced by oxaliplatin: description of three cases.

Case reports in oncology 2012 Jan;5;104-9 — 2012 Jan — 104-9