The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.e

ARDS - Acute lung injury

Publications

Aggarwal NR, Brower RG

Targeting normoxemia in acute respiratory distress syndrome may cause worse short-term outcomes because of oxygen toxicity.

Annals of the American Thoracic Society 2014 Nov;11;1449-53 — 2014 Nov — 1449-53

Thomson L, Paton J

Oxygen toxicity.

Paediatric respiratory reviews 2014 Jun;15;120-3 — 2014 Jun — 120-3

Louge P, Cantais E, Palmier B

[Acute respiratory distress syndrome after prolonged hyperbaric oxygen therapy: a case of pulmonary oxygen toxicity?].

Annales francaises d'anesthesie et de reanimation 2001 Jun;20;559-62 — 2001 Jun — 559-62

Case records of the Massachusetts General Hospital. Case 7-1967.

The New England journal of medicine 1967 Feb 16;276;401-11 — 1967 Feb 16 — 401-11

Nash G, Blennerhassett JB, Pontoppidan H

Pulmonary lesions associated with oxygen therapy and artifical ventilation.

The New England journal of medicine 1967 Feb 16;276;368-74 — 1967 Feb 16 — 368-74

Kapanci Y, Tosco R, Eggermann J, Gould VE

Oxygen pneumonitis in man., Light- and electron-microscopic morphometric studies.

Chest 1972 Aug;62;162-9 — 1972 Aug — 162-9

Clark JM, Lambertsen CJ

Pulmonary oxygen toxicity: a review.

Pharmacological reviews 1971 Jun;23;37-133 — 1971 Jun — 37-133

Barber RE, Hamilton WK

Oxygen toxicity in man. A prospective study in patients with irreversible brain damage.

The New England journal of medicine 1970 12 31;283;1478-84 — 1970 12 31 — 1478-84

Jackson RM

Pulmonary oxygen toxicity.

Chest 1985 Dec;88;900-5 — 1985 Dec — 900-5

Ingrassia TS, Ryu JH, Trastek VF, Rosenow EC

Oxygen-exacerbated bleomycin pulmonary toxicity.

Mayo Clinic proceedings 1991 Feb;66;173-8 — 1991 Feb — 173-8

Saussine M, Colson P, Alauzen M, Mary H

Postoperative acute respiratory distress syndrome. A complication of amiodarone associated with 100 percent oxygen ventilation.

Chest 1992 Sep;102;980-1 — 1992 Sep — 980-1