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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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XV.bd

Path: Bronchiolar necrosis & vasculitis

Last update : 01/01/1970
 

Causative drugs

1

Sauropus androgynus

IV.c IV - Airway involvement
IV.c - Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)
IV.k IV - Airway involvement
IV.k - Bronchiectasis
IV.n IV - Airway involvement
IV.n - Obstructive airway dysfunction (see also IVc, XVx)
XII.t XII - Cardiovascular involvement / toxicity
XII.t - Torsades de pointe
XV.z XV - Pathology
XV.z - Path: Obliterative (constrictive) bronchiolitis (see also IVc, IVn)
XV.bb XV - Pathology
XV.bb - Path: Airway inflammation
XV.bd XV - Pathology
XV.bd - Path: Bronchiolar necrosis & vasculitis
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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