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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Sauropus androgynus

4

XV.z Path: Obliterative (constrictive) bronchiolitis (see also IVc, IVn)

3
Last update : 27/01/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
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Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Herbals - Dietary botanical therapy - Health products/food - Plants
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Publications

Retransplantation of contralateral lung in a patient with Sauropus androgynus-induced bronchobronchiolitis obliterans.
Transplantation proceedings 2000 Nov;32;2432-4 2000 Nov
Sauropus androgynus-constrictive obliterative bronchitis/bronchiolitis--histopathological study of pneumonectomy and biopsy specimens with emphasis on the inflammatory process and disease progression.
Histopathology 2000 Nov;37;402-10 2000 Nov
Segmental necrosis of small bronchi after prolonged intakes of Sauropus androgynus in Taiwan.
American journal of respiratory and critical care medicine 1998 Feb;157;594-8 1998 Feb
Histopathological study of Sauropus androgynus-associated constrictive bronchiolitis obliterans: a new cause of constrictive bronchiolitis obliterans.
The American journal of surgical pathology 1997 Jan;21;35-42 1997 Jan

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