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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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XV.aq

Path: Resin (Kayexalate-Sevelamer) lung

Last update : 01/01/1970
 

Causative drugs

2

Kayexalate

II.b II - Pulmonary edema - Acute lung injury - ARDS
II.b - ARDS - Acute lung injury
IV.i IV - Airway involvement
IV.i - Foreign body aspiration bronchiolitis
XI.g XI - Miscellaneous
XI.g - Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)
XV.aq XV - Pathology
XV.aq - Path: Resin (Kayexalate-Sevelamer) lung
1

Sevelamer

IV.i IV - Airway involvement
IV.i - Foreign body aspiration bronchiolitis
XV.aq XV - Pathology
XV.aq - Path: Resin (Kayexalate-Sevelamer) lung
1
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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