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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Kayexalate

2

XI.g Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)

2
Last update : 17/06/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Refractory hypoxemia due to sodium polystyrene sulfonate (kayexalate) aspiration.
Annals of the American Thoracic Society 2014 Jul;11;993-5 2014 Jul
Pulmonary disease due to aspiration of food and other particulate matter: a clinicopathologic study of 59 cases diagnosed on biopsy or resection specimens.
The American journal of surgical pathology 2007 May;31;752-9 2007 May
Kayexalate (sodium polystyrene sulfonate) aspiration.
Archives of pathology & laboratory medicine 2005 Jan;129;125 2005 Jan

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