v2.2
Contact
News
Diagnosing DIRD
Browse
Available on AppStore
The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
Browse by »
Drugs
Patterns
VI.q
Rebound pulmonary arterial hypertension
Upon sudden vasodilator drug discontinuation or withdrawal
Last update :
01/01/1970
Causative drugs
2
Nitric oxide (NO)
II.a
II - Pulmonary edema - Acute lung injury - ARDS
II.a - Pulmonary edema, noncardiogenic (NCPE)
II.f
II - Pulmonary edema - Acute lung injury - ARDS
II.f - Hypoxemia, low oxygen saturation (may occur in isolation)
VI.q
VI - Pulmonary vasculopathies
VI.q - Rebound pulmonary arterial hypertension
XIV.a
XIV - Hemoglobinopathies - Abnormal hemoglobin states (acquired)
XIV.a - Methemoglobinemia
1
Prostacyclin
I.b
I - Interstitial/parenchymal lung disease
I.b - Pneumonitis (ILD)
II.a
II - Pulmonary edema - Acute lung injury - ARDS
II.a - Pulmonary edema, noncardiogenic (NCPE)
II.d
II - Pulmonary edema - Acute lung injury - ARDS
II.d - Pulmonary edema, cardiogenic
VI.i
VI - Pulmonary vasculopathies
VI.i - Acute pulmonary hypertension
VI.q
VI - Pulmonary vasculopathies
VI.q - Rebound pulmonary arterial hypertension
1
1
Search
Search
Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist