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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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XI.l

Superior vena cava syndrome

Last update : 01/01/1970
 

Causative drugs

1

Ethylene-vinyl alcohol copolymer (e.g. Onyx (R))

II.a II - Pulmonary edema - Acute lung injury - ARDS
II.a - Pulmonary edema, noncardiogenic (NCPE)
II.b II - Pulmonary edema - Acute lung injury - ARDS
II.b - ARDS - Acute lung injury
II.f II - Pulmonary edema - Acute lung injury - ARDS
II.f - Hypoxemia, low oxygen saturation (may occur in isolation)
VI.v VI - Pulmonary vasculopathies
VI.v - Foreign body/substance pulmonary embolism
XI.l XI - Miscellaneous
XI.l - Superior vena cava syndrome
1
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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