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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Ethylene-vinyl alcohol copolymer (e.g. Onyx (R))

1
Last update : 18/02/2017
II - Pulmonary edema - Acute lung injury - ARDS

II.a Pulmonary edema, noncardiogenic (NCPE)

1

II.b ARDS - Acute lung injury

1

II.f Hypoxemia, low oxygen saturation (may occur in isolation)

1
VI - Pulmonary vasculopathies

VI.v Foreign body/substance pulmonary embolism

1
XI - Miscellaneous

XI.l Superior vena cava syndrome

1
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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