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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Ethylene-vinyl alcohol copolymer (e.g. Onyx (R))

1

VI.v Foreign body/substance pulmonary embolism

1
Last update : 03/05/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

A Case Report of Onyx Pulmonary Arterial Embolism Contributing to Hypoxemia During Awake Craniotomy for Arteriovenous Malformation Resection.
A & A case reports 2017 Feb 15;8;86-88 2017 Feb 15
Onyx pulmonary artery embolization after treatment of a low-flow dural arteriovenous fistula: case report.
Neurosurgery 2011 May;68;E1497-500; discussion E1500 2011 May

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