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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Barotrauma

5

III.a Alveolar hemorrhage (AH), diffuse AH (DAH)

2
Last update : 29/10/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Forceful inspiration against a closed glottis or airway
4
Mechanical ventilation (invasive)
5
Mechanical ventilation (noninvasive)
1

Publications

Negative-pressure acute tracheobronchial hemorrhage and pulmonary edema.
Journal of anesthesia 2009;23;417-20 2009
Pulmonary hemorrhage associated with negative-pressure pulmonary edema.
Anesthesiology 2000 Sep;93;888-90 2000 Sep

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