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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amoxicillin

4

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

4
Last update : 05/07/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Antibiotics
5
Beta-lactam antibiotics
5
Penicillins
5

Publications

Massive Facial, Neck, and Chest Air Leaks after Amoxicillin-related Anaphylaxis in a Young Child.
American journal of respiratory and critical care medicine 2020 Apr 01;201;859-860 2020 Apr 01
Anaphylaxis to beta-lactam antibiotics at pediatric age: Six-year survey.
Allergologia et immunopathologia 2019;47;128-132 2019
Severe drug-induced anaphylaxis: analysis of 333 cases recorded by the Allergy Vigilance Network from 2002 to 2010.
Allergy 2013 Jul;68;929-37 2013 Jul
Adverse reaction to amoxicillin: a case report.
Pediatric dentistry 2000;22;401-4 2000

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