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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Excipients-Vehicle-Preservatives (of drugs)

5

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1
Last update : 24/01/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Amiodarone
5
Benzylbenzoate
1
Cremophor
1
Crospovidone
2
Preservatives
2
Ricin (Castor oil)
2
Sesame oil
1
Soybean
1
Talc (inhaled, sniffed, i.v., intrapleural)
3

Publications

The use of beclomethasone diproprionate inhaler complicated by the development of an eosinophilic pneumonia reaction.
Annals of allergy 1977 Aug;39;133-6 1977 Aug
Loeffler's syndrome; occurrence in two patients treated with penicillin in oil and wax.
Journal of the American Medical Association 1949 Sep 03;141;21 1949 Sep 03

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