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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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  • Drugs
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Abused drugs/substances (illicit-, street drugs - IV/inhaled)

5

VIII.ai Nasal, palatal and/or pharyngeal pathology

3
Last update : 03/02/2019
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Amphetamine (and -derivatives)
3
Amyl-nitrite, butyl-nitrite, isobutyl-nitrite ('Poppers')
4
Antidotes
1
Body packing
4
Cannabinoids - Cannabinoid receptor agonists (synthetic) (K2, Spice)
5
Cathinones, synthetic ('Bath salts')
5
Cocaine
5
Crack cocaine
5
E-cigarette - E-vaporizers - ENDS - Vaping - Dabbing
5
E-cigarette's, e-vaporizer's secondhand vapor (Passive vaping)
1
Excipients-Vehicle-Preservatives (of drugs)
5
Heroin (inhaled, insufflated, snorted)
4
Heroin (intravenous)
5
Inhalants (volatile substances)
5
Marijuana, cannabis (haschish, hash, bang, dab)
5
Methadone
5
Opiates - Opioids - Opium
5
Recreational drugs
5
Sniffed drugs (opioids, acetaminophen)
5
Talc (inhaled, sniffed, i.v., intrapleural)
3
Warfarin
5

Publications

Intranasal drug-induced fungal rhinopharyngitis.
International forum of allergy & rhinology 2012;2;130-4 2012
[Palatal necrosis due to cocaine abuse].
Revue de stomatologie et de chirurgie maxillo-faciale 2010 Feb;111;32-5 2010 Feb
Cocaine-induced midline destructive lesions mimicking ENT-limited Wegener's granulomatosis.
Scandinavian journal of rheumatology 2008;37;477-80 2008
[A patient with both cocaine-induced nasal septum destruction and antibodies against anti-neutrophil cytoplasmic antibodies (ANCA); potential confusion with Wegener's disease].
Nederlands tijdschrift voor geneeskunde 2007 Oct 27;151;2395-9 2007 Oct 27
Cocaine-related syndrome and palatal reconstruction: report of a series of cases.
International journal of oral and maxillofacial surgery 2007 Aug;36;721-7 2007 Aug
Aggressive destructive midfacial lesion from cocaine abuse.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2002 Oct;94;465-70 2002 Oct
Progressive septal and palatal perforation secondary to intranasal cocaine abuse.
The Medical journal of Malaysia 1998 Dec;53;435-8 1998 Dec
Nasal cocaine abuse mimicking midline granuloma.
Journal of the American Academy of Dermatology 1995 Feb;32;286-7 1995 Feb
Nasal cocaine abuse causing an aggressive midline intranasal and pharyngeal destructive process mimicking midline reticulosis and limited Wegener's granulomatosis.
The Journal of rheumatology 1990 Jun;17;838-40 1990 Jun

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