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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cocaine

5

XII.l Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

2
Last update : 04/01/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5
Crack cocaine
5
Levamisole
4
Levamisole-adulterated/tainted cocaine
5
Talc (inhaled, sniffed, i.v., intrapleural)
3

Publications

Electrocardiographic findings associated with cocaine use in humans: a systematic review.
Expert review of cardiovascular therapy 2012 Jan;10;105-27 2012 Jan
Hemodynamic and arrhythmogenic effects of cocaine in hypertensive individuals.
Journal of clinical hypertension (Greenwich, Conn.) 2011 Oct;13;744-9 2011 Oct
Asthma deaths confounded by substance abuse. An assessment of fatal asthma.
Chest 1996 Sep;110;604-10 1996 Sep

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