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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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  • Drugs
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Cocaine

5

II.a Pulmonary edema, noncardiogenic (NCPE)

2
Last update : 18/04/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5
Crack cocaine
5
Levamisole
4
Levamisole-adulterated/tainted cocaine
5
Talc (inhaled, sniffed, i.v., intrapleural)
3

Publications

Clinical review: Major consequences of illicit drug consumption.
Critical care (London, England) 2008;12;202 2008
Cocaine-induced fatal acute eosinophilic pneumonia: a case report.
WMJ : official publication of the State Medical Society of Wisconsin 2007 Apr;106;92-5 2007 Apr
Cocaine and pulmonary oedema.
Anaesthesia 2003 Mar;58;285-6 2003 Mar
Stimulant-induced pulmonary toxicity.
Chest 1995 Oct;108;1140-9 1995 Oct
A review of the respiratory effects of smoking cocaine.
The American journal of medicine 1989 Dec;87;664-8 1989 Dec
Pulmonary edema in cocaine smokers.
Radiology 1989 Aug;172;463-5 1989 Aug

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