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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cocaine

5

III.b Pneumorenal syndrome (w/wo ANCAs)

2
Last update : 11/04/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5
Crack cocaine
5
Levamisole
4
Levamisole-adulterated/tainted cocaine
5
Talc (inhaled, sniffed, i.v., intrapleural)
3

Publications

Contaminated cocaine and antineutrophil cytoplasmic antibody-associated disease.
Clinical journal of the American Society of Nephrology : CJASN 2011 Dec;6;2799-805 2011 Dec
Alveolar hemorrhage in anti-basement membrane antibody disease: a series of 28 cases.
Medicine 2007 May;86;181-193 2007 May

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