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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Bupropion, bupropion poisoning

2

X.a DRES syndrome - DRESS-like reaction

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Drug-induced rash with eosinophilia and systemic symptoms syndrome with bupropion administration.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2003 May;90;572-5 2003 May

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