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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Penicillins

5

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 08/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Amoxicillin
4
Antibiotics
5
Cefazolin
1
Cefotiam
1
Cefpodoxime
1
Ceftaroline
1
Ceftriaxone
1
Cephalexin
1
Cephalosporin(s)
3

Publications

Immediate allergic reactions to beta-lactams: diagnosis and therapy.
International journal of immunopathology and pharmacology 2003;16;19-23 2003
Drug-induced attack of bronchial asthma in inpatients: a 20-year survey of the Comprehensive Hospital Drug Monitoring Programme on adverse drug reactions, Berne/St. Gallen.
European journal of clinical pharmacology 1997;53;81-2 1997
[Occupational asthma caused by allergy to penicillin].
Archives des maladies professionnelles de medecine du travail et de securite sociale 1960;21;13-23 1960

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