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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Penicillins

5

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

5
Last update : 30/10/2018
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Amoxicillin
4
Antibiotics
5
Cefazolin
1
Cefotiam
1
Cefpodoxime
1
Ceftaroline
1
Ceftriaxone
1
Cephalexin
1
Cephalosporin(s)
3

Publications

Anaphylaxis mortality in the perioperative setting: Epidemiology, elicitors, risk factors and knowledge gaps.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2024 Jan;54;11-20 2024 Jan
Drug-Induced Anaphylaxis Documented in Electronic Health Records.
The journal of allergy and clinical immunology. In practice 2019 Jan;7;103-111 2019 Jan
An update on epidemiology of anaphylaxis in children and adults.
Current opinion in allergy and clinical immunology 2011 Oct;11;492-6 2011 Oct
Clinical practice. Antibiotic allergy.
The New England journal of medicine 2006 Feb 09;354;601-9 2006 Feb 09
Drug-induced anaphylaxis : case/non-case study based on an italian pharmacovigilance database.
Drug safety 2005;28;547-56 2005
Risk of anaphylaxis in a hospital population in relation to the use of various drugs: an international study.
Pharmacoepidemiology and drug safety 2003;12;195-202 2003
Anaphylaxis to penicillin on reperfusion during liver transplantation.
Anesthesiology 2000 Jul;93;280-1 2000 Jul
Anaphylaxis in labor secondary to prophylaxis against group B Streptococcus. A case report.
The Journal of reproductive medicine 1999 Apr;44;381-4 1999 Apr
Severe anaphylactic reaction to penicillin during halothane anaesthesia. A case report.
British journal of anaesthesia 1971 Apr;43;410-2 1971 Apr
FATAL SYSTEMIC ANAPHYLAXIS IN MAN.
The New England journal of medicine 1964 Mar 19;270;597-603 1964 Mar 19
Dangers in the use of some potent drugs.
Canadian Medical Association journal 1962 Dec 15;87;1275-81 1962 Dec 15
[On the pathogenesis of hemorrhagic phenomena during anaphylactic shock from penicillin].
Minerva medica 1959 Oct 31;50;3482-9 1959 Oct 31
Anaphylactic shock and death due to penicillin; report of a case.
Annals of allergy 1954;12;453-4 1954
Fatal anaphylaxis in bronchial asthma following administration of penicillin; report of two cases with autopsy findings.
New York state journal of medicine 1953 May 01;53;1107-10 1953 May 01

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