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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Paraffin-Vaseline-Oil-Lipids (Mineral or other) p.o./inhaled/aspirated

5

XV.p Path: Exogenous lipoid pneumonia

1
Last update : 20/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Camphor
1
Excipients-Vehicle-Preservatives (of drugs)
5
Hydrocarbons (petrochemicals: petroleum, petrolatum, paraffin, vaseline, naphta, jet fuel (kerosene), Diesel, gasoil), ointments, salad oil, variegated oils, butter). Aspirated
5
Oil - Paraffin - Lipids (i.v.)
5
Oil-/lipid-based formulations (parenteral)
3
Olive oil
1
Ricin (Castor oil)
2
Sesame oil
1
Shark oil
2
Soybean
1
Vaseline
1
Vicks Vaporub TM (R)
2

Publications

[Exogenous lipid pneumonia].
Annales de pathologie 2024 Nov;44;498-504 2024 Nov
[Exogenous lipoid pneumonia and anorexia nervosa: a case report].
Anales del sistema sanitario de Navarra 2022 Aug 16;45; 2022 Aug 16
Presenting Clinicoradiologic Features, Causes, and Clinical Course of Exogenous Lipoid Pneumonia in Adults.
Chest 2021 Aug;160;624-632 2021 Aug
Exogenous lipoid pneumonia: an important cause of interstitial lung disease in infants.
Respirology case reports 2018 Oct;6;e00356 2018 Oct
Exogenous lipoid pneumonia. Clinical and radiological manifestations.
Respiratory medicine 2011 May;105;659-66 2011 May
Not your typical pneumonia: a case of exogenous lipoid pneumonia.
Journal of general internal medicine 2007 Nov;22;1613-6 2007 Nov
Exogenous lipoid pneumonia: importance of clinical history to the diagnosis.
Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 2006;32;596-8 2006
Lipoid pneumonia: a silent complication of mineral oil aspiration.
Pediatrics 1999 Feb;103;E19 1999 Feb
Exogenous lipid pneumonia: a retrospective multicentre study of 44 cases in France.
The European respiratory journal 1996 Jul;9;1463-9 1996 Jul
Exogenous lipoid pneumonia.
Archives of internal medicine 1994 Mar 28;154;686-92 1994 Mar 28
Successful treatment of diffuse lipoid pneumonitis with whole lung lavage.
Thorax 1993 Sep;48;947-8 1993 Sep
Occult mineral oil pneumonitis in anorexia nervosa.
The Western journal of medicine 1988 Feb;148;211-3 1988 Feb
Clinical conference in pulmonary disease. Aspiration and occult esophageal disorders.
Chest 1981 Oct;80;489-95 1981 Oct
Studies on Pneumonia Following Naso-Pharyngeal Injections of Oil.
The American journal of pathology 1925 Jul;1;407-414.1 1925 Jul

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