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Vicks Vaporub TM (R)

A trade mark (Al Aboud K. The founder of Vicks: Lunsford Richardson (1854-1919). Skinmed 2010; 8: 100 - PMID 20527143). An oil-based formulation containing camphor, menthol, cedar oil, eucalyptus, turpentine, thymol, and vaseline

Last update : 02/02/2022

I.j Exogenous lipoid pneumonia (subacute, acute)

I.ap Paraffinoma - Lipidoma (ELP in the form of a nodule or mass)

VIII.d Thermal (burns, frostbite), chemical or caustic injury on the face, mouth, tongue, pharynx or upper airway

X.u Multiple organ dysfunction/failure (MODS/MOF)

XII.l Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

XV.p Path: Exogenous lipoid pneumonia

XIX.h BAL: Exogenous (oil red O-stainable) lipids in BAL macrophages

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

More detailed checklist

The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France