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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Paraffin-Vaseline-Oil-Lipids (Mineral or other) p.o./inhaled/aspirated

5

I.z An area or areas of consolidation

2
Last update : 27/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Camphor
1
Excipients-Vehicle-Preservatives (of drugs)
5
Hydrocarbons (petrochemicals: petroleum, petrolatum, paraffin, vaseline, naphta, jet fuel (kerosene), Diesel, gasoil), ointments, salad oil, variegated oils, butter). Aspirated
5
Oil - Paraffin - Lipids (i.v.)
5
Oil-/lipid-based formulations (parenteral)
3
Olive oil
1
Ricin (Castor oil)
2
Sesame oil
1
Shark oil
2
Soybean
1
Vaseline
1
Vicks Vaporub TM (R)
2

Publications

Lipoid pneumonia: a challenging diagnosis.
Heart & lung : the journal of critical care 2011;40;580-4 2011
Lipoid pneumonia presenting as non resolving community acquired pneumonia: a case report.
Cases journal 2009 Dec 16;2;9332 2009 Dec 16
Lipoid pneumonia: a preventable form of drug-induced lung injury.
European journal of internal medicine 2005 Dec;16;615-7 2005 Dec
Exogenous lipoid pneumonia.
Archives of internal medicine 1994 Mar 28;154;686-92 1994 Mar 28

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