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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Oil-/lipid-based formulations (parenteral)

3

VI.e Fat/oil embolism - The FES embolism syndrome

2
Last update : 21/02/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anabolic androgenic steroids
3
Doxorubicin (pegylated-liposomal)
1
Excipients, erroneously/deliberately administered i.v.
5
Excipients-Vehicle-Preservatives (of drugs)
5
Lipiodol - Iodinated/iodized oil (RCM)
2
Olive oil
1
Progesterone
2
Synthol
2
Testosterone cypionate
1
Testosterone undecanoate
3

Publications

Occurrence of Pulmonary Oil Microembolism After Testosterone Undecanoate Injection: A Postmarketing Safety Analysis.
Sexual medicine 2020 Jun;8;237-242 2020 Jun
Pulmonary oil micro-embolism (POME) syndrome: a review and summary of a large case series.
Current medical research and opinion 2015 Apr;31;837-41 2015 Apr
[The usage of synthol in the body building].
Polimery w medycynie 2009;39;63-5 2009

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