The Drug-Induced Respiratory Disease Website and App
Frequency - Incidence
Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases
Evidence level/grade
Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic
Hemolytic and uremic syndrome (HUS). See also under Xaf
Publications
A review of hemolytic uremic syndrome in patients treated with gemcitabine therapy.
Cancer 1999 May 01;85;2023-32 — 1999 May 01 — 2023-32
Thrombotic microangiopathy associated with chemotherapy: case report and review of the literature.
DICP : the annals of pharmacotherapy 1989 Jul-Aug;23;582-8 — 1989 Jul-Aug — 582-8