The Drug-Induced Respiratory Disease Website and App

Beta-2 agonists, B2 mimetics (parenteral)

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

XLI.a

Pulmonary edema, noncardiogenic (NCPE)

The respective role of tocolytic agents, underlying cardiac disease, fluid overload, and preeclampsia must be evaluated

Publications

Hamel H, Bonniaud P, Baudouin N, Spagnolo G, Sagot P, Camus P

[Pulmonary edema and tocolysis with beta-agonists].

Revue des maladies respiratoires 2002 Apr;19;241-4 — 2002 Apr — 241-4

Lamont RF

The pathophysiology of pulmonary oedema with the use of beta-agonists.

BJOG : an international journal of obstetrics and gynaecology 2000 Apr;107;439-44 — 2000 Apr — 439-44

Clesham GJ

Beta adrenergic agonists and pulmonary oedema in preterm labour.

BMJ (Clinical research ed.) 1994 Jan 22;308;260-2 — 1994 Jan 22 — 260-2

Davies AE, Robertson MJ

Pulmonary oedema after the administration of intravenous salbutamol and ergometrine. Case report.

British journal of obstetrics and gynaecology 1980 Jun;87;539-41 — 1980 Jun — 539-41

Nimrod CA, Beresford P, Frais M, Belenkie I, Tyberg J, Fremit A, Smith E

Hemodynamic observations on pulmonary edema associated with a beta-mimetic agent. A report of two cases.

The Journal of reproductive medicine 1984 May;29;341-4 — 1984 May — 341-4

Mabie WC, Pernoll ML, Witty JB, Biswas MK

Pulmonary edema induced by betamimetic drugs.

Southern medical journal 1983 Nov;76;1354-60 — 1983 Nov — 1354-60

Guernsey BG, Villarreal Y, Snyder MD, Gabert HA

Pulmonary edema associated with the use of betamimetic agents in preterm labor.

American journal of hospital pharmacy 1981 Dec;38;1942-8 — 1981 Dec — 1942-8

Turner E, Rathgeber J, Kittel E, Grospietsch G, Braun U

[Fenoterol (Partusisten)-associated lung edema. A case report].

Der Anaesthesist 1986 Apr;35;258-60 — 1986 Apr — 258-60

Russi EW, Spaetling L, Gmür J, Schneider H

High permeability pulmonary edema (ARDS) during tocolytic therapy--a case report.

Journal of perinatal medicine 1988;16;45-9 — 1988 — 45-9

Milos M, Aberle DR, Parkinson BT, Batra P, Brown K

Maternal pulmonary edema complicating beta-adrenergic therapy of preterm labor.

AJR. American journal of roentgenology 1988 Nov;151;917-8 — 1988 Nov — 917-8

Pisani RJ, Rosenow EC

Pulmonary edema associated with tocolytic therapy.

Annals of internal medicine 1989 May 01;110;714-8 — 1989 May 01 — 714-8