The Drug-Induced Respiratory Disease Website and App

Frequency - Incidence

Incidence of respiratory adverse event(s) due to the specific drug as assessed by number of reported/published cases in the literature. Red digits in stars indicate: 0 = Very rare, questionable signal · 1 = < 10 cases · 2 = 10-50 cases · 3 = 50–100 cases · 4 = 100-200 cases · 5 = >200 cases

Evidence level/grade

Evidence level for respiratory adverse event(s) due to the specific drug as estimated using Hill’s (1965), Naranjo’s (1981), and Bégaud’s (1985) criteria applied to published cases. Blue digits in stars indicate: 0 = Questionable · 1 = Low · 2 = Moderate · 3 = Robust · 4 = Definite · 5 = Unquestionable, pathognomonic

II.e

ARDS - Acute lung injury

Publications

Rego EM, De Santis GC

Differentiation syndrome in promyelocytic leukemia: clinical presentation, pathogenesis and treatment.

Mediterranean journal of hematology and infectious diseases 2011;3;e2011048 — 2011 — e2011048

Beer TM, Tangen CM, Nichols CR, Margolin KA, Dreicer R, Stephenson WT, Quinn DI, Raghavan D, Crawford ED

Southwest Oncology Group phase II study of arsenic trioxide in patients with refractory germ cell malignancies.

Cancer 2006 Jun 15;106;2624-9 — 2006 Jun 15 — 2624-9

Hassaballa HA, Lateef OB, Silver MR, Balk RA

Acute lung injury induced by arsenic trioxide in a patient with refractory myelodysplastic syndrome.

Journal of critical care 2005 Mar;20;111-3 — 2005 Mar — 111-3